@article {144,
	title = {Pyrethrins combined with piperonyl butoxide (RID) vs 1\% permethrin (NIX) in the treatment of head lice},
	journal = {American Journal of Diseases of Children},
	volume = {142},
	year = {1988},
	note = {LR: 20041117; JID: 0370471; 0 (Drug Combinations); 0 (Pyrethrins); 0 (RID); 51-03-6 (Piperonyl Butoxide); 52645-53-1 (Permethrin); ppublish},
	month = {1988},
	pages = {768 - 769},
	abstract = {In a randomized controlled trial, 58 subjects were treated for Pediculus humanus var capitis with either pyrethrins combined with piperonyl butoxide (RID, Pfizer Inc, New York) or 1\% permethrin (NIX, Burroughs Wellcome Co, Research Triangle Park, NC); 31 subjects received RID and 27 subjects received NIX. Both products were applied according to manufacturer{\textquoteright}s directions so that NIX was applied only on the first visit and RID was applied on the first visit and again seven days later. After each treatment with a pediculicide, the comb supplied by the manufacturer was used to remove nits. Seven days after the initial visit, NIX was determined to be significantly better than RID for eradicating the lice infestation. Of the 27 subjects receiving NIX, 26 were live free vs 14 of the 31 RID-treated subjects. At day 14, there was no statistically significant difference in the treatments (27 of 27 NIX-treated vs 29 of 31 RID-treated subjects were lice free). The RID comb was superior to the NIX comb for nit removal. Both treatments were effective and well tolerated, and no subject experienced adverse reactions.},
	keywords = {adolescent, adult, animals, child, Child, Preschool, Comparative Study, Drug Combinations/therapeutic use, Drug Evaluation, humans, Lice Infestations/drug therapy, Pediculus, Permethrin, Piperonyl Butoxide, Pyrethrum, Random Allocation, Research Support, Non-U.S. Gov{\textquoteright}t, scalp},
	url = {http://www.phthiraptera.info/Publications/45388.pdf},
	author = {Carson,D. S. and Tribble,P. W. and Weart,C. W.}
}
@article {110,
	title = {Treatment of Pediculus humanus var. capitis infestation in Cowlitz County, Washington, with ivermectin and the LiceMeister(R) comb},
	journal = {Pediatric Infectious Disease Journal},
	volume = {17},
	year = {1998},
	month = {1998},
	pages = {923 - 924},
	keywords = {adolescent, adult, animals, child, Child, Preschool, humans, insecticide, Insecticide Resistance, Ivermectin/therapeutic use, Lice Infestations/drug therapy, Pediculus, Permethrin, Pyrethrum, scalp dermatoses, Washington},
	author = {Bell,T. A.}
}
@article {59,
	title = {Efficacy of a reduced application time of Ovide lotion (0.5\% malathion) compared to Nix creme rinse (1\% permethrin) for the treatment of head lice},
	journal = {Pediatric dermatology},
	volume = {21},
	year = {2004},
	note = {JID: 8406799; 0 (Insecticides); 121-75-5 (Malathion); 52645-53-1 (Permethrin); ppublish},
	month = {2004},
	pages = {670 - 674},
	address = {United States},
	abstract = {Our objective was to conduct a randomized, investigator-blinded evaluation of the pediculicidal and ovicidal activity of a reduced application time (20 minutes) of Ovide (0.5\% malathion) compared to Nix (1\% permethrin) in a south Florida population infested with Pediculus humanus capitis. Either Ovide or Nix was applied according to the label instructions. However, Ovide application time was reduced to 20 minutes. At day 8, subjects with live lice were re-treated with the same product and procedure as on day 1. Ovicidal and pediculicidal efficacy were evaluated at days 8 and 15. A subject free of lice and viable eggs at day 15 was considered to be a treatment success. Percent efficacy was calculated using the number of subjects free of lice and viable eggs per total number of subjects treated. We found that a 20-minute application of Ovide was significantly more pediculicidal and ovicidal (98\%) compared to Nix (55\%) at day 15 (p < 0.0001). The percentage of Ovide subjects who required treatment at day 8 was half that of the Nix group. The reinfestation rate was 0\% with Ovide and 33\% with Nix. In conclusion, a 20-minute treatment with Ovide, instead of the approved 8- to 12-hour application, cured 40 of 41 subjects (98\%), demonstrating superior efficacy to Nix. The poor efficacy of Nix confirms the resistance of head lice to permethrin in south Florida.},
	keywords = {adolescent, adult, Aged, animals, child, Comparative Study, Dose-Response, Florida, humans, insecticide, Lice Infestations/drug therapy, malathion, Middle Aged, Pediculus, Permethrin, Research Support, Non-U.S. Gov{\textquoteright}t, scalp dermatoses, Single-Blind Method, Treatment Outcome},
	isbn = {0736-8046},
	author = {Meinking,Terri Lynn and Vicaria,M. and Eyerdam,D. H. and Villar,M. E. and Reyna,S. and Suarez,G.}
}
