@article {173,
	title = {Malathion for treatment of Pediculus humanus var capitis infestation},
	journal = {JAMA : the journal of the American Medical Association},
	volume = {247},
	year = {1982},
	note = {LR: 20041117; JID: 7501160; 0 (Vehicles); 121-75-5 (Malathion); ppublish},
	month = {1982},
	pages = {3103 - 3105},
	address = {UNITED STATES},
	abstract = {One hundred fifteen subjects took part in a double-blind study comparing the efficacy and safety of 0.5\% malathion lotion (Prioderm lotion) and the alcoholic vehicle of the lotion as pediculicides in the treatment of head lice. The subjects, with a mean age of 9 years, had long-standing lice infestations and at least 20 viable ova. The subjects were treated with the test preparation, which was allowed to remain on the hair for 12 hours. Ovicidal and pediculicidal efficacy for the malathion lotion was significant; overall clinical evaluation by the investigators showed a significant number of moderate to marked therapeutic responses to malathion lotion. Only one adverse reaction (in the malathion lotion group) was reported, the stinging of pyodermal lesions in reaction to the alcoholic vehicle. Other concomitant scalp diseases were unchanged or improved at the end of the study.},
	keywords = {Administration, Topical, adolescent, adult, child, Child, Preschool, Clinical Trials, Double Blind, Drug Resistance, hair, humans, Lice Infestations/drug therapy, malathion, Ovum/drug effects, Pediculus, Pyoderma, Random Allocation, scalp dermatoses, Vehicles},
	isbn = {0098-7484},
	author = {Taplin,David and Castillero,P. M. and Spiegel,J. and Mercer,S. and Rivera,A. A. and Schachner,L.}
}
@article {110,
	title = {Treatment of Pediculus humanus var. capitis infestation in Cowlitz County, Washington, with ivermectin and the LiceMeister(R) comb},
	journal = {Pediatric Infectious Disease Journal},
	volume = {17},
	year = {1998},
	month = {1998},
	pages = {923 - 924},
	keywords = {adolescent, adult, animals, child, Child, Preschool, humans, insecticide, Insecticide Resistance, Ivermectin/therapeutic use, Lice Infestations/drug therapy, Pediculus, Permethrin, Pyrethrum, scalp dermatoses, Washington},
	author = {Bell,T. A.}
}
@article {86,
	title = {A preliminary pilot survey on head lice, pediculosis in Sharkia Governorate and treatment of lice with natural plant extracts},
	journal = {Journal of the Egyptian Society of Parasitology},
	volume = {32},
	year = {2002},
	note = {LR: 20041117; JID: 8102141; 0 (Plant Extracts); ppublish},
	month = {2002},
	pages = {725 - 736},
	address = {Egypt},
	abstract = {Twelve different representative areas in Sharkia Governorate were surveyed for head lice, Pediculus humanus capitis. The pre-valence was investigated among 120 houses containing 2,448 individual, with different age, sex and socioeconomic status. Examination was done by naked eye aided with hand-lens. A total of 137 individuals were infested. Infestation rates were higher in the rural areas with low socioeconomic levels, concrete houses with over-crowded family members. Children had significantly higher infestation rates than adults. Males had lower infestation rates than females. However, the hair length and permanent hair washing were the factors accounted for both age and sex difference in prevalence of pediculosis. Head lice infestations were found all over the year, but increased in summer and spring. One hundred infested patients (90 females and 10 males) with different aged and hair length were treated with tour mixed cream from plants Lawsonia alba L. (Henna). Trigonella faemum-gracanum (Fenugreek), Hibiscus cannabinus (Hibiscus) and Artemisia cina (Wormseed). The head lice completely disappeared within a week among those patients treated by henna mixed with aqueous extract of sheah (100\%) or mixed with helba (75\%) or with karkada (50\%).},
	keywords = {adolescent, adult, Age Distribution, animals, child, Child, Preschool, Egypt, Hibiscus/chemistry, humans, Infant, Lawsonia Plant/chemistry, Lice Infestations/drug therapy/epidemiology, Pediculus, Phytotherapy, Pilot Projects, Plant Extracts, prevalence, scalp dermatoses, Seasons, Sex Distribution, Trigonella/chemistry},
	isbn = {0253-5890},
	author = {El-Basheir,Z. M. and Fouad,M. A.}
}
@article {59,
	title = {Efficacy of a reduced application time of Ovide lotion (0.5\% malathion) compared to Nix creme rinse (1\% permethrin) for the treatment of head lice},
	journal = {Pediatric dermatology},
	volume = {21},
	year = {2004},
	note = {JID: 8406799; 0 (Insecticides); 121-75-5 (Malathion); 52645-53-1 (Permethrin); ppublish},
	month = {2004},
	pages = {670 - 674},
	address = {United States},
	abstract = {Our objective was to conduct a randomized, investigator-blinded evaluation of the pediculicidal and ovicidal activity of a reduced application time (20 minutes) of Ovide (0.5\% malathion) compared to Nix (1\% permethrin) in a south Florida population infested with Pediculus humanus capitis. Either Ovide or Nix was applied according to the label instructions. However, Ovide application time was reduced to 20 minutes. At day 8, subjects with live lice were re-treated with the same product and procedure as on day 1. Ovicidal and pediculicidal efficacy were evaluated at days 8 and 15. A subject free of lice and viable eggs at day 15 was considered to be a treatment success. Percent efficacy was calculated using the number of subjects free of lice and viable eggs per total number of subjects treated. We found that a 20-minute application of Ovide was significantly more pediculicidal and ovicidal (98\%) compared to Nix (55\%) at day 15 (p < 0.0001). The percentage of Ovide subjects who required treatment at day 8 was half that of the Nix group. The reinfestation rate was 0\% with Ovide and 33\% with Nix. In conclusion, a 20-minute treatment with Ovide, instead of the approved 8- to 12-hour application, cured 40 of 41 subjects (98\%), demonstrating superior efficacy to Nix. The poor efficacy of Nix confirms the resistance of head lice to permethrin in south Florida.},
	keywords = {adolescent, adult, Aged, animals, child, Comparative Study, Dose-Response, Florida, humans, insecticide, Lice Infestations/drug therapy, malathion, Middle Aged, Pediculus, Permethrin, Research Support, Non-U.S. Gov{\textquoteright}t, scalp dermatoses, Single-Blind Method, Treatment Outcome},
	isbn = {0736-8046},
	author = {Meinking,Terri Lynn and Vicaria,M. and Eyerdam,D. H. and Villar,M. E. and Reyna,S. and Suarez,G.}
}
